Beilstein J. Org. Chem.2020,16, 2911–2919, doi:10.3762/bjoc.16.240
autofluorescence of the peptide or protein. Here, we demonstrate the use of UVRR spectroscopy with 244 nm laser excitation for the characterization of GCP as well as guanidiniocarbonylindole (GCI), a next generation supramolecular ligand for the recognition of carboxylates. For demonstrating the feasibility of
the results from density functional theory (DFT) calculations.
Keywords: GCI; GCP; guanidiniocarbonylindole; guanidiniocarbonyl pyrrole; UVRR; Raman spectroscopy; resonance Raman; Introduction
Supramolecular ligands are capable to selectively bind to peptides and proteins via reversible non
supramolecular ligands: guanidiniocarbonyl pyrrole (GCP) and guanidiniocarbonylindole (GCI). The latter class of artificial carboxylate receptors is a potential next generation binder based on the GCI motif which maintains the good carboxylate binding properties of GCP. GCI comprises an indole ring instead of a
PDF
Graphical Abstract
Figure 1:
UV–vis absorption spectra of GCP ethyl amide [9] (in grey) and GCI ethyl amide (in green) at 200 µM co...